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Review
. 2017 Dec;96(49):e8651.
doi: 10.1097/MD.0000000000008651.

A primary cavernous hemangioma of the thyroid gland: A case report and literature review

Jie Miao  1 , Shubo Chen, Yongcai Li, Lin Fu, Hui Li
Affiliations
Review

A primary cavernous hemangioma of the thyroid gland: A case report and literature review

Jie Miao et al. Medicine (Baltimore). 2017 Dec.

Abstract

Rationale: Thyroid hemangioma is benign and associated with fine-needle aspiration (FNA) biopsy or trauma in most cases. Its differential diagnosis is very difficult.

Patient concerns: We presented the case of a 48-year-old man complained of slowly progressed swelling in the anterior neck for 20 years.

Diagnoses: Ultrasound and CT scan revealed a hypoechogenic and heterogeneous mass measuring 4 × 3.5 cm located in the right lobe of thyroid gland. Postoperative pathological and immunohistochemical examinations of the surgical specimen revealed a primary hemangioma of the thyroid gland.

Interventions: The patient received a right lobectomy of the thyroid.

Outcomes: The patient had been followed up for 10 months after surgery without complications and remained asymptomatic.

Lessons: Primary thyroid hemangioma should be considered when there is a well-circumscribed capsule mass on medical imaging without history of FNA or any other cervical procedures or trauma.

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Conflict of interest statement

The authors report no conflicts of interest.

Figures

Figure 1
Figure 1
Microscopic view of the thyroid hemangioma. (A, B) On histopathology, the lesion consisted of multiple irregular, dilated vessel lumens filled with red blood cells and hemorrhagic zone, resulting in the atrophy of the adjacent thyroid tissue. (A) a. Image of the excised tumor. b. Thyroid tissues. c. Vessel lumens. (B) a. Hemorrhagic areas. b. Thyroid tissues. (C, E) Immunohistochemical staining showed strongly immunoreactive for thyroid transcription factor-1 in the thyroid tissue. (D, F) Immunohistochemical staining showed that the hemangioma was strongly positive for CD34. Bar: 50 μm.
See this image and copyright information in PMC

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