Response to Immune Checkpoint Blockade is Influenced by HLA-I Genotype
- PMID: 29247014
- DOI: 10.1158/2159-8290.CD-RW2017-236
Response to Immune Checkpoint Blockade is Influenced by HLA-I Genotype
Abstract
Maximal HLA-I loci heterozygosity is linked to improved survival after immune checkpoint blockade.
©2018 American Association for Cancer Research.
Comment on
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Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy.Science. 2018 Feb 2;359(6375):582-587. doi: 10.1126/science.aao4572. Epub 2017 Dec 7. Science. 2018. PMID: 29217585 Free PMC article.
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