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Case Reports
. 2017 Dec 17;11(1):350.
doi: 10.1186/s13256-017-1516-8.

Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report

Montassar Ghalleb  1 , Hatem Bouzaiene  1 , Skander Slim  2 , Achraf Hadiji  1 , Monia Hechiche  1 , Jamel Ben Hassouna  1 , Khaled Rahal  1
Affiliations
Case Reports

Fertility-sparing surgery in advanced stage malignant ovarian germ cell tumor: a case report

Montassar Ghalleb et al. J Med Case Rep. .

Abstract

Background: Malignant ovarian germ cell tumor is a rare type of disease, which generally has a good prognosis due to the high chemosensitivity of this type of tumor. Fertility preservation is an important issue because malignant ovarian germ cell tumor commonly affects young women. Although conservation is the standard for early stage, it becomes more debatable as the disease progresses to more advanced stages.

Aim: Report the case of a patient with an International Federation of Gynecology and Obstetrics Stage IIIc malignant ovarian germ cell tumor, who had conservative surgery and chemotherapy with a good fertility outcome.

Case presentation: A 23-year-old North African woman with a left malignant ovarian germ cell tumor stage IIIc was treated by left adnexectomy and omentectomy followed by chemotherapy. A 15-year follow-up showed no signs of relapse, and she completed three full-term natural pregnancies.

Conclusions: Malignant ovarian germ cell tumor is a rare ovarian tumor with a good prognosis. It is usually associated with a good fertility outcome in early stages. However, due to the rarity of the disease in advanced stages, the fertility outcome for this group of patients is not clear. This lack of data surrounding advanced stages points to the need for a meta-analysis of all published cases.

Keywords: Fertility; Malignant germ line tumor; Surgery.

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Conflict of interest statement

Ethics approval and consent to participate

We declare no conflicts of interest between the authors and that this work was made with all due respect to the code of ethics under the supervision of the medical and ethic committee of the Salah Azaiez Institute.

Consent for publication

Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.

Competing interests

The authors declare that they have no competing interests.

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