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Comment
. 2018 Feb;41(2):74-76.
doi: 10.1016/j.tins.2017.12.001. Epub 2017 Dec 14.

A Peek into Parkinson's Disease Progression through Human Dopamine Neurons in a Dish

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A Peek into Parkinson's Disease Progression through Human Dopamine Neurons in a Dish

Nan Yang et al. Trends Neurosci. 2018 Feb.

Abstract

Using induced human dopamine (DA) neurons, a study by Burbulla and colleagues demonstrated a toxic cascade of cellular dysfunctions which may underlie Parkinson's disease (PD) progression. Their findings reveal what could be the causal relationship between multiple pathogenic pathways in human neurons obtained from idiopathic and familial cases, and suggest novel targets for therapeutic intervention.

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