Point-of-care diagnostics for respiratory viral infections

doi:10.1080/14737159.2018.1419065

Review

. 2018 Jan;18(1):75-83.

doi: 10.1080/14737159.2018.1419065. Epub 2017 Dec 26.

Point-of-care diagnostics for respiratory viral infections

Kerri Basile^{1

2}, Jen Kok^{1

2}, Dominic E Dwyer^{1

2}

Affiliations

¹ a Centre for Infectious Diseases and Microbiology Laboratory Services , Institute of Clinical Pathology and Medical Research, NSW Health Pathology , Westmead , Australia.
² b Marie Bashir Institute for Emerging Infections and Biosecurity , University of Sydney, Westmead Hospital , Westmead , Australia.

PMID: 29251007
PMCID: PMC7103700
DOI: 10.1080/14737159.2018.1419065

Review

Point-of-care diagnostics for respiratory viral infections

Kerri Basile et al. Expert Rev Mol Diagn. 2018 Jan.

. 2018 Jan;18(1):75-83.

doi: 10.1080/14737159.2018.1419065. Epub 2017 Dec 26.

Authors

Kerri Basile^{1

2}, Jen Kok^{1

2}, Dominic E Dwyer^{1

2}

Affiliations

¹ a Centre for Infectious Diseases and Microbiology Laboratory Services , Institute of Clinical Pathology and Medical Research, NSW Health Pathology , Westmead , Australia.
² b Marie Bashir Institute for Emerging Infections and Biosecurity , University of Sydney, Westmead Hospital , Westmead , Australia.

PMID: 29251007
PMCID: PMC7103700
DOI: 10.1080/14737159.2018.1419065

Abstract

Successful treatment outcomes for viral respiratory tract infections presenting from primary health care to quaternary hospitals will only be achieved with rapid, sensitive and specific identification of pathogens to allow effective pathogen-specific antiviral therapy and infection control measures. Areas covered: This review aims to explore the different point-of-care tests currently available to diagnose viral respiratory tract infections, discuss the advantages and limitations of point-of-care testing, and provide insights into the future of point-of-care tests. The following databases were searched: Medline (January 1996 to 30 September 2017) and Embase (1988 to 30 September 2017), using the following keywords: 'point of care', 'respiratory virus', 'influenza', 'RSV', 'diagnostics', 'nucleic acid test' and 'PCR'. Expert commentary: Viral respiratory tract infections cause significant morbidity and mortality worldwide, and point-of-care tests are facilitating the rapid identification of the pathogen responsible given the similarities in clinical presentation.

Keywords: Point-of-care; diagnostics; respiratory viruses.

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References

1. Macintyre CR, Heywood AE, Kovoor P, et al. Ischaemic heart disease, influenza and influenza vaccination: a prospective case control study. Heart. 2013;99:1843–1848. - PMC - PubMed
1. Data Compendium 2011 ed. Available from: http://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trend... Centers for Medicare and Medicaid Services.
1. Newall AT, Wood JG, Macintyre CR.. Influenza-related hospitalisation and death in Australians aged 50 years and older. Vaccine. 2008;26:2135–2141. - PMC - PubMed
1. Tillett HE, Smith JW, Gooch CD.. Excess deaths attributable to influenza in England and Wales: age at death and certified cause. Int J Epidemiol. 1983;12:344–352. - PubMed
1. Mese S, Akan H, Badur S, et al. Analytical performance of the BD veritor system for rapid detection of influenza virus A and B in a primary healthcare setting. BMC Infect Dis. 2016;16:481. - PMC - PubMed

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[1] Macintyre CR, Heywood AE, Kovoor P, et al. Ischaemic heart disease, influenza and influenza vaccination: a prospective case control study. Heart. 2013;99:1843–1848. - PMC - PubMed

[2] Macintyre CR, Heywood AE, Kovoor P, et al. Ischaemic heart disease, influenza and influenza vaccination: a prospective case control study. Heart. 2013;99:1843–1848. - PMC - PubMed

[3] Data Compendium 2011 ed. Available from: http://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trend... Centers for Medicare and Medicaid Services.

[4] Data Compendium 2011 ed. Available from: http://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trend... Centers for Medicare and Medicaid Services.

[5] Newall AT, Wood JG, Macintyre CR.. Influenza-related hospitalisation and death in Australians aged 50 years and older. Vaccine. 2008;26:2135–2141. - PMC - PubMed

[6] Newall AT, Wood JG, Macintyre CR.. Influenza-related hospitalisation and death in Australians aged 50 years and older. Vaccine. 2008;26:2135–2141. - PMC - PubMed

[7] Tillett HE, Smith JW, Gooch CD.. Excess deaths attributable to influenza in England and Wales: age at death and certified cause. Int J Epidemiol. 1983;12:344–352. - PubMed

[8] Tillett HE, Smith JW, Gooch CD.. Excess deaths attributable to influenza in England and Wales: age at death and certified cause. Int J Epidemiol. 1983;12:344–352. - PubMed

[9] Mese S, Akan H, Badur S, et al. Analytical performance of the BD veritor system for rapid detection of influenza virus A and B in a primary healthcare setting. BMC Infect Dis. 2016;16:481. - PMC - PubMed

[10] Mese S, Akan H, Badur S, et al. Analytical performance of the BD veritor system for rapid detection of influenza virus A and B in a primary healthcare setting. BMC Infect Dis. 2016;16:481. - PMC - PubMed

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Point-of-care diagnostics for respiratory viral infections

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Point-of-care diagnostics for respiratory viral infections

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