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Editorial
. 2018;17(4):397-398.
doi: 10.1080/15384101.2017.1415668. Epub 2018 Feb 8.

Apoptosis inhibitor 5: Role in the inhibition of caspase-2

Gergely Imre  1 , Krishnaraj Rajalingam  1
Affiliations
Editorial

Apoptosis inhibitor 5: Role in the inhibition of caspase-2

Gergely Imre et al. Cell Cycle. 2018.
No abstract available

Keywords: API5; apoptosis; apoptosis Inhibitor 5; caspase-2; cell death; pore forming toxins.

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Figures

Figure 1.
Figure 1.
API5 directly binds to the CARD domain of caspase-2 and prevents the dimerization possibly in the cytosol. This leads to inactivation of caspase-2 and prevention of PFT-mediated apoptotic cell death.
See this image and copyright information in PMC

Comment on

References

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