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. 1989 Apr;108(4):1221-6.
doi: 10.1083/jcb.108.4.1221.

Induction and characterization of mitochondrial DNA mutants in Chlamydomonas reinhardtii

R F Matagne  1 , M R Michel-Wolwertz, C Munaut, C Duyckaerts, F Sluse
Affiliations

Induction and characterization of mitochondrial DNA mutants in Chlamydomonas reinhardtii

R F Matagne et al. J Cell Biol. 1989 Apr.

Abstract

In addition to lethal minute colony mutations which correspond to loss of mitochondrial DNA, acriflavin induces in Chlamydomonas reinhardtii a low percentage of cells that grow in the light but do not divide under heterotrophic conditions. Two such obligate photoautotrophic mutants were shown to lack the cyanide-sensitive cytochrome pathway of the respiration and to have a reduced cytochrome c oxidase activity. In crosses to wild type, the mutations are transmitted almost exclusively from the mating type minus parent. A same pattern of inheritance is seen for the mitochondrial DNA in crosses between the two interfertile species C. reinhardtii and Chlamydomonas smithii. Both mutants have a deletion in the region of the mitochondrial DNA containing the apocytochrome b gene and possibly the unidentified URFx gene.

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References

    1. Proc Natl Acad Sci U S A. 1985 May;82(10):3340-4 - PubMed
    1. EMBO J. 1986 Jan;5(1):21-8 - PubMed
    1. Proc Natl Acad Sci U S A. 1987 Apr;84(8):2391-5 - PubMed
    1. Curr Genet. 1987;12(1):41-7 - PubMed
    1. Nature. 1985 Apr 18-24;314(6012):592-7 - PubMed