Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Dec;22(50):17-00121.
doi: 10.2807/1560-7917.ES.2017.22.50.17-00121.

Secular trends in incidence of acute gastroenteritis in general practice, France, 1991 to 2015

Mathieu Rivière  1   2 , Noémie Baroux  1 , Vanina Bousquet  3 , Katia Ambert-Balay  4 , Pascal Beaudeau  3 , Nathalie Jourdan-Da Silva  3 , Dieter Van Cauteren  3 , Frédéric Bounoure  5 , Fanny Cahuzac  1 , Thierry Blanchon  1 , Thierry Prazuck  1   2 , Clément Turbelin  1 , Thomas Hanslik  1   6
Affiliations

Secular trends in incidence of acute gastroenteritis in general practice, France, 1991 to 2015

Mathieu Rivière et al. Euro Surveill. 2017 Dec.

Abstract

We analysed 25 years of general practitioner (GP) visits for acute gastroenteritis (AG) surveillance in France, by the GP Sentinelles network. We searched for time trends of acute gastroenteritis incidence during winter periods. Data from emergency departments and drug reimbursement were additional data sources. A time-series analysis was performed using a generalised additive model for all data sources for the winter period. Virological data were incorporated and compared with the three data sources. The cumulative incidence of GP visits for winter AG exhibited an increasing trend from 1991 until 2008, when it reached 6,466 per 100,000 inhabitants. It decreased thereafter to 3,918 per 100,000 inhabitants in 2015. This decreasing trend was observed for all age groups and confirmed by the generalised additive model. For emergency department visits a decreasing trend was observed from 2004. Drug reimbursement data analyses demonstrated a decreasing trend from when data began in 2009. The incidence reported by GPs and emergency departments was lower following the emergence of norovirus GII.4 2012 (p < 0.0001). Winter AG incidences seem to follow long-term rising and decreasing trends that are important to monitor through continuous surveillance to evaluate the impact of prevention strategies, such as future immunisation against acute viral gastroenteritis.

Keywords: France; gastrointestinal illness; sentinel surveillance; trend.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Weekly incidence rates of acute gastroenteritis general practitioner visits, drug reimbursement data, weekly proportion of emergency department visits for acute gastroenteritis, and predominant circulating strain of rotavirus and norovirus (National Reference Center for Gastroenteritis Viruses), France, 1991–2015
Figure 2
Figure 2
Acute gastroenteritis trends for general practitioner visits data, emergency department visits and drug reimbursement data using the estimated spline term value of a generalised additive model, France, 1991/1992 to 2014/2015 season
Figure 3
Figure 3
Cumulative incidence rates of general practitioner visits for winter acute gastroenteritis, by geographic area, Sentinelles network, France, 2009/10 to 2014/15
Figure 4
Figure 4
Cumulative incidence rates of general practitioner visits for winter influenza-like illness and chickenpox, Sentinelles network, France, 1991/1992 to 2014/2015 season
See this image and copyright information in PMC

References

    1. Majowicz SE, Hall G, Scallan E, Adak GK, Gauci C, Jones TF, et al. A common, symptom-based case definition for gastroenteritis. Epidemiol Infect. 2008;136(7):886-94. 10.1017/S0950268807009375 - DOI - PMC - PubMed
    1. Boschi-Pinto C, Velebit L, Shibuya K. Estimating child mortality due to diarrhoea in developing countries. Bull World Health Organ. 2008;86(9):710-7. 10.2471/BLT.07.050054 - DOI - PMC - PubMed
    1. Van Cauteren D, De Valk H, Vaux S, Le Strat Y, Vaillant V. Burden of acute gastroenteritis and healthcare-seeking behaviour in France: a population-based study. Epidemiol Infect. 2012;140(4):697-705. 10.1017/S0950268811000999 - DOI - PubMed
    1. Huet F, Chouchane M, Cremillieux C, Aubert M, Caulin E, Pothier P, et al. [Prospective epidemiological study of rotavirus gastroenteritis in Europe (REVEAL study). Results in the French area of the study]. Arch Pediatr. 2008;15(4):362-74. 10.1016/j.arcped.2008.01.021 - DOI - PubMed
    1. Arena C, Amoros JP, Vaillant V, Ambert-Balay K, Chikhi-Brachet R, Jourdan-Da Silva N, et al. Acute diarrhea in adults consulting a general practitioner in France during winter: incidence, clinical characteristics, management and risk factors. BMC Infect Dis. 2014;14(1):574. 10.1186/s12879-014-0574-4 - DOI - PMC - PubMed

MeSH terms

LinkOut - more resources