Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Dec;22(50):17-00767.
doi: 10.2807/1560-7917.ES.2017.22.50.17-00767.

Influenza A(H3N2) virus variants and patient characteristics during a summer influenza epidemic in Taiwan, 2017

Tsung-Pei Tsou  1 , Chia-Ping Su  2   3 , Wan-Ting Huang  2 , Ji-Rong Yang  4 , Ming-Tsan Liu  4
Affiliations

Influenza A(H3N2) virus variants and patient characteristics during a summer influenza epidemic in Taiwan, 2017

Tsung-Pei Tsou et al. Euro Surveill. 2017 Dec.

Abstract

We report a summer influenza epidemic caused by co-circulation of multiple influenza A(H3N2) variants in clade 3C.2a. Compared with other clades, a putative clade 3C.2a.3a was more commonly isolated from severely ill patients; 3C.2a.4 was more commonly isolated in outbreak cases. Time from vaccination to illness onset was significantly shorter in severely ill patients infected with clade 3C.2a.3; characteristics and outcomes of patients infected with different clades were similar. No resistance to antiviral medications was found.

Keywords: epidemiology; influenza; influenza virus; laboratory surveillance; vaccine-preventable diseases.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Phylogenetic relationship and amino acid changes of the influenza A(H3N2) virus haemagglutinin gene, Taiwan, 1 July 2016–15 July 2017
Figure 2
Figure 2
Influenza A(H3N2) viruses findings from the National Influenza Laboratory Surveillance Network, Taiwan, 1 July 2016–15 July 2017
Figure 3
Figure 3
Number of influenza A(H3N2) virus isolates by clade and patient source, Taiwan, 1 July 2016–15 July 2017
See this image and copyright information in PMC

References

    1. Skowronski DM, Chambers C, Sabaiduc S, Dickinson JA, Winter AL, De Serres G, et al. Interim estimates of 2016/17 vaccine effectiveness against influenza A(H3N2), Canada, January 2017. Euro Surveill. 2017;22(6):30460. 10.2807/1560-7917.ES.2017.22.6.30460 - DOI - PMC - PubMed
    1. Trebbien R, Fischer TK, Krause TG, Nielsen L, Nielsen XC, Weinreich LS, et al. Changes in genetically drifted H3N2 influenza A viruses and vaccine effectiveness in adults 65 years and older during the 2016/17 season in Denmark. J ClinVirol. 2017;94:1-7. 10.1016/j.jcv.2017.06.007 - DOI - PubMed
    1. Glatman-Freedman A, Drori Y, Beni SA, Friedman N, Pando R, Sefty H, et al. Genetic divergence of Influenza A(H3N2) amino acid substitutions mark the beginning of the 2016-2017 winter season in Israel. J ClinVirol. 2017;93:71-5. 10.1016/j.jcv.2017.05.020 - DOI - PMC - PubMed
    1. Harvala H, Frampton D, Grant P, Raffle J, Ferns RB, Kozlakidis Z, et al. ICONIC Consortium Emergence of a novel subclade of influenza A(H3N2) virus in London, December 2016 to January 2017. Euro Surveill. 2017;22(8):30466. 10.2807/1560-7917.ES.2017.22.8.30466 - DOI - PMC - PubMed
    1. Melidou A, Broberg E, European region influenza surveillance network Predominance of influenza A(H3N2) virus genetic subclade 3C.2a1 during an early 2016/17 influenza season in Europe - Contribution of surveillance data from World Health Organization (WHO) European Region to the WHO vaccine composition consultation for northern hemisphere 2017/18. Vaccine. 2017;35(37):4828-35. 10.1016/j.vaccine.2017.07.057 - DOI - PubMed

MeSH terms

Substances

LinkOut - more resources