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. 2017 May 16;16(3):276-282.
doi: 10.1002/rmb2.12036. eCollection 2017 Jul.

Clinical outcomes of infertility treatment for women with adenomyosis in Japan

Hiroshi Tamura  1 , Hiroshi Kishi  2 , Mari Kitade  3 , Mikiko Asai-Sato  4 , Atsushi Tanaka  5 , Takashi Murakami  6 , Takashi Minegishi  2 , Norihiro Sugino  1
Affiliations

Clinical outcomes of infertility treatment for women with adenomyosis in Japan

Hiroshi Tamura et al. Reprod Med Biol. .

Abstract

Aim: A multicenter, retrospective survey was conducted in order to investigate the current clinical status of adenomyosis in Japan.

Methods: The questionnaires covered the management of infertile women with adenomyosis and the outcomes of infertility treatment in women with adenomyosis. The questionnaires were sent to 1149 facilities in Japan.

Results: The data were obtained on 535 infertile women with adenomyosis from 190 facilities. Regarding management, infertility treatment was performed without pretreatment for adenomyosis in 37 facilities, after medication in eight facilities, and after an operation in four facilities. Management policies were not established in 106 facilities. Regarding outcomes, the pregnancy rate was 41.7% and the abortion rate was 29.8%. Eighty-five patients received medication and 89 patients underwent surgery as a pretreatment before infertility treatment, while 361 patients had no pretreatment. In relation to the type of adenomyosis, 162 patients had the focal type and 336 patients had the diffuse type. The pregnancy rate and abortion rate were not affected by pretreatment or the type of adenomyosis.

Conclusion: The management policy for infertile women with adenomyosis has not been established. The pregnancy rate of infertility treatment is about 40%. There were no data to suggest that medication or surgery as a pretreatment for adenomyosis increased the pregnancy rate in infertile women.

Keywords: adenomyosis; infertility; miscarriage; pregnancy rate; surgery.

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Figure 1
Figure 1
Flow diagram and the clinical outcomes of infertility treatment
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