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Review
. 2017 Dec 19;90(4):653-659.
eCollection 2017 Dec.

Genome Editing: Past, Present, and Future

Dana Carroll  1
Affiliations
Review

Genome Editing: Past, Present, and Future

Dana Carroll. Yale J Biol Med. .

Abstract

The CRISPR-Cas genome editing tools have been adopted rapidly in the research community, and they are quickly finding applications in the commercial sector as well. Lest we lose track of the broader context, this Perspective presents a brief review of the history of the genome editing platforms and considers a few current technological issues. It then takes a very limited view into the future of this technology and highlights some of the societal issues that require examination and discussion.

Keywords: CRISPR-Cas; DNA repair; Genome editing; TALENs; zinc-finger nucleases.

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