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Book

Notalgia Paresthetica

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Notalgia Paresthetica

Blake A. Robbins et al.
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Excerpt

Notalgia paresthetica is a chronic neuropathic dysesthesia of unknown etiology characterized by pruritus located on the medial border of the inferior scapula. The condition was first described by the Russian neurologist Michail Astwazaturow in 1934 and is usually benign. Irritation or damage to thoracic nerves two to six have been implicated as causative, but the exact location of damage has not been elucidated. Most studies attribute thoracic polyradiculopathy due to spinal nerve compression as the primary etiology behind the pruritus.

Others state the anatomical angle of sensory nerve fiber penetration through the surrounding muscle is the cause. Notalgia paresthetica is typically seen in older females, is unilateral, and can last for months to years. There are no primary cutaneous lesions, only secondary changes due to chronic scratching. Diagnosis through history and physical is typically sufficient, but occasionally, further imaging may be required. Treatment remains disappointing, and oral neurologic modulators, such as gabapentin, are reported to be the most efficacious therapy.[8]

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Conflict of interest statement

Disclosure: Blake Robbins declares no relevant financial relationships with ineligible companies.

Disclosure: Appaji Rayi declares no relevant financial relationships with ineligible companies.

Disclosure: Sarah Ferrer-Bruker declares no relevant financial relationships with ineligible companies.

References

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    1. Šitum M, Kolić M, Franceschi N, Pećina M. NOTALGIA PARESTHETICA. Acta Clin Croat. 2018 Dec;57(4):721-725. - PMC - PubMed
    1. Raison-Peyron N, Meunier L, Acevedo M, Meynadier J. Notalgia paresthetica: clinical, physiopathological and therapeutic aspects. A study of 12 cases. J Eur Acad Dermatol Venereol. 1999 May;12(3):215-21. - PubMed
    1. da Cruz CM, Antunes F. Physical Medicine and Rehabilitation Role on Notalgia Paresthetica: Case Report and Treatment Review. Am J Phys Med Rehabil. 2018 Dec;97(12):929-932. - PubMed
    1. Alai NN, Skinner HB. Concurrent notalgia paresthetica and brachioradial pruritus associated with cervical degenerative disc disease. Cutis. 2018 Sep;102(3):185;186;189;190. - PubMed

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