Mitral Valve Prolapse
- PMID: 29262039
- Bookshelf ID: NBK470288
Mitral Valve Prolapse
Excerpt
Mitral valve prolapse (MVP), also known as floppy mitral valve syndrome, systolic click-murmur syndrome, and billowing mitral leaflets, is a valvular heart disease disorder (see Image. Mitral Valve Prolapse). It is a benign condition. In rare cases, it may present with sudden cardiac death, endocarditis, or a stroke. The condition affects nearly 3% of the United States population. The disorder produces symptoms due to a redundant and abnormally thickened mitral valve leaflet prolapsing into the left atrium during systole. MVP is usually identified during a clinical exam on cardiac auscultation. Echocardiography confirms the diagnosis. This disorder is the most common cause of the non-ischemic mitral valve is mitral regurgitation in the US. Symptomatic patients may need mitral valve repair.
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Sections
- Continuing Education Activity
- Introduction
- Etiology
- Epidemiology
- Pathophysiology
- Histopathology
- History and Physical
- Evaluation
- Treatment / Management
- Differential Diagnosis
- Prognosis
- Complications
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References
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- Nalliah CJ, Mahajan R, Elliott AD, Haqqani H, Lau DH, Vohra JK, Morton JB, Semsarian C, Marwick T, Kalman JM, Sanders P. Mitral valve prolapse and sudden cardiac death: a systematic review and meta-analysis. Heart. 2019 Jan;105(2):144-151. - PubMed
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- Ayme-Dietrich E, Lawson R, Da-Silva S, Mazzucotelli JP, Monassier L. Serotonin contribution to cardiac valve degeneration: new insights for novel therapies? Pharmacol Res. 2019 Feb;140:33-42. - PubMed
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- Hayek E, Gring CN, Griffin BP. Mitral valve prolapse. Lancet. 2005 Feb 5-11;365(9458):507-18. - PubMed
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