Skin Biopsy
- PMID: 29262109
- Bookshelf ID: NBK470457
Skin Biopsy
Excerpt
A skin biopsy is an important diagnostic procedure commonly performed in dermatology practices. Various methods of skin biopsies exist, and multiple factors are considered in choosing the most appropriate biopsy technique for a given situation. Among the most important factors are location, depth, and breadth of sampling. An effort is made to provide the consulting pathologist with an adequate amount of tissue from the site most likely to yield a diagnosis while minimizing disfigurement and preserving the patient’s function as much as possible.
Biopsies are categorized as either incisional, where only a portion of a lesion is sampled, or excisional, where the entire visible lesion is removed. An incisional biopsy can be performed using shave, scissor, curettage, or punch techniques. An excisional biopsy is typically performed with a full-thickness scalpel excision or a deeper oblique (shave or scoop) excision.
Copyright © 2025, StatPearls Publishing LLC.
Conflict of interest statement
Sections
References
-
- Yang S, Kampp J. Common Dermatologic Procedures. Med Clin North Am. 2015 Nov;99(6):1305-21. - PubMed
-
- Elston DM, Stratman EJ, Miller SJ. Skin biopsy: Biopsy issues in specific diseases. J Am Acad Dermatol. 2016 Jan;74(1):1-16; quiz 17-8. - PubMed
-
- Iyengar S, Yeager DG, Cohen JL, Ozog DM. Update and Review of Bleeding Considerations in Dermatologic Surgery: Anticoagulants and Antiplatelets. Dermatol Surg. 2020 Feb;46(2):192-201. - PubMed
-
- McKay W, Morris R, Mushlin P. Sodium bicarbonate attenuates pain on skin infiltration with lidocaine, with or without epinephrine. Anesth Analg. 1987 Jun;66(6):572-4. - PubMed
-
- Lin WL, Wu LM, Nguyen TH, Lin YH, Chen CJ, Huang WT, Guo HR, Chen YH, Chuang CH, Chang PC, Hung HK, Chen SH. Topical Antibiotic Prophylaxis for Preventing Surgical Site Infections of Clean Wounds: A Systematic Review and Meta-Analysis. Surg Infect (Larchmt) 2024 Feb;25(1):32-38. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Medical