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Editorial
. 2018 Mar 15;197(6):706-707.
doi: 10.1164/rccm.201712-2368ED.

Float Like Bacilli, STING Like a B: Type I Interferons in Tuberculosis

Joel D Ernst  1
Affiliations
Editorial

Float Like Bacilli, STING Like a B: Type I Interferons in Tuberculosis

Joel D Ernst. Am J Respir Crit Care Med. .
No abstract available

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Comment on

  • B Cells Producing Type I IFN Modulate Macrophage Polarization in Tuberculosis.
    Bénard A, Sakwa I, Schierloh P, Colom A, Mercier I, Tailleux L, Jouneau L, Boudinot P, Al-Saati T, Lang R, Rehwinkel J, Loxton AG, Kaufmann SHE, Anton-Leberre V, O'Garra A, Sasiain MDC, Gicquel B, Fillatreau S, Neyrolles O, Hudrisier D. Bénard A, et al. Am J Respir Crit Care Med. 2018 Mar 15;197(6):801-813. doi: 10.1164/rccm.201707-1475OC. Am J Respir Crit Care Med. 2018. PMID: 29161093 Free PMC article.

References

    1. Bénard A, Sakwa I, Schierloh P, Colom A, Mercier I, Tailleux L, et al. B cells producing type I IFN modulate macrophage polarization in tuberculosis Am J Respir Crit Care Med 2018197801–813 - PMC - PubMed
    1. Manca C, Tsenova L, Bergtold A, Freeman S, Tovey M, Musser JM, et al. Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-α/β. Proc Natl Acad Sci USA. 2001;98:5752–5757. - PMC - PubMed
    1. Wiens KE, Ernst JD. The mechanism for type I interferon induction by Mycobacterium tuberculosis is bacterial strain-dependent. PLoS Pathog. 2016;12:e1005809. - PMC - PubMed
    1. Mayer-Barber KD, Andrade BB, Barber DL, Hieny S, Feng CG, Caspar P, et al. Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection. Immunity. 2011;35:1023–1034. - PMC - PubMed
    1. Novikov A, Cardone M, Thompson R, Shenderov K, Kirschman KD, Mayer-Barber KD, et al. Mycobacterium tuberculosis triggers host type I IFN signaling to regulate IL-1β production in human macrophages. J Immunol. 2011;187:2540–2547. - PMC - PubMed

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