Genomic medicine in the military

Mauricio De Castro¹, Leslie G Biesecker², Clesson Turner³, Ruth Brenner⁴, Catherine Witkop⁴, Maxwell Mehlman^{5

6}, Chris Bradburne⁷, Robert C Green⁸

Affiliations

¹ United States Air Force Medical Genetics Center, 81st Medical Group, Keesler AFB, Biloxi, MS, USA.
² National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
³ Walter Reed National Medical Center, Division of Genetics, Department of Pediatrics, United States Army, Bethesda, MD, USA.
⁴ Air Force Medical Support Agency, Defense Health Headquarters, Falls Church, VA, USA.
⁵ Law-Medicine center, Case Western Reserve University School of Law, Cleveland, OH, USA.
⁶ Department of Biomedical ethics, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
⁷ National Security Systems Biology Center, Asymmetric Operations Sector, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA.
⁸ Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Partners Personalized Medicine, Broad Institute and Harvard Medical School, Boston, MA, USA.

PMID: 29263806
PMCID: PMC5685294
DOI: 10.1038/npjgenmed.2015.8

Editorial

Genomic medicine in the military

Mauricio De Castro et al. NPJ Genom Med. 2016.

. 2016 Jan 13:1:15008.

doi: 10.1038/npjgenmed.2015.8. eCollection 2016.

Authors

Mauricio De Castro¹, Leslie G Biesecker², Clesson Turner³, Ruth Brenner⁴, Catherine Witkop⁴, Maxwell Mehlman^{5

6}, Chris Bradburne⁷, Robert C Green⁸

Affiliations

¹ United States Air Force Medical Genetics Center, 81st Medical Group, Keesler AFB, Biloxi, MS, USA.
² National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
³ Walter Reed National Medical Center, Division of Genetics, Department of Pediatrics, United States Army, Bethesda, MD, USA.
⁴ Air Force Medical Support Agency, Defense Health Headquarters, Falls Church, VA, USA.
⁵ Law-Medicine center, Case Western Reserve University School of Law, Cleveland, OH, USA.
⁶ Department of Biomedical ethics, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
⁷ National Security Systems Biology Center, Asymmetric Operations Sector, Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA.
⁸ Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Partners Personalized Medicine, Broad Institute and Harvard Medical School, Boston, MA, USA.

PMID: 29263806
PMCID: PMC5685294
DOI: 10.1038/npjgenmed.2015.8

Abstract

The announcement of the Precision Medicine Initiative was an important step towards establishing the use of genomic information as part of the wider practice of medicine. The US military has been exploring the role that genomic information will have in health care for service members (SMs) and its integration into the continuum of military medicine. An important part of the process is establishing robust protections to protect SMs from genetic discrimination in the era of exome/genome sequencing.

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Conflict of interest statement

The authors declare no conflict of interest.

References

1. Collins, F. S. & Varmus, H. A new initiative on precision medicine. N. Engl. J. Med. 372, 793–795 (2015). - PMC - PubMed
1. Biesecker, L. G. & Green, R. C. Diagnostic clinical genome and exome sequencing. N. Engl. J. Med. 371, 1170 (2014). - PubMed
1. U.S. Department of Defense. DOD directive 5154.24, Armed Forces Institute of Pathology (2007).
1. U.S. Department of Defense. Hemoglobin S and Erythrocyte Glucose 6 Phosphate Dehydrogenase Deficiency Testing Program (1981).
1. Webber, B. J. & Witkop, C. T. Screening for sickle-cell trait at accession to the United States military. Mil. Med. 179, 1184–1189 (2014). - PubMed

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Genomic medicine in the military

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Genomic medicine in the military

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