Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Dec 16;216(suppl_10):S912-S918.
doi: 10.1093/infdis/jix431.

Pathogenesis of Non-Zika Congenital Viral Infections

Suresh B Boppana  1 , William J Britt  1 , Karen Fowler  1 , S Cecelia Hutto  1 , Scott H James  1 , David W Kimberlin  1 , Claudette Poole  1 , Shannon A Ross  1 , Richard J Whitley  1
Affiliations
Review

Pathogenesis of Non-Zika Congenital Viral Infections

Suresh B Boppana et al. J Infect Dis. .

Abstract

A widespread epidemic of Zika virus (ZIKV) infection was reported in 2015 from South and Central America and the Caribbean. Although the full spectrum of ZIKV infection of the newborn has yet to be determined, other maternal viral infections resulting in transmission to the fetus provide instructive lessons that can be applied to the prospective evaluation of individuals with ZIKV infection. This review focuses on those other congenital infections, including rubella, congenital cytomegalovirus, human immunodeficiency virus, hepatitis B virus, and neonatal herpes simplex virus, from which lessons for the evaluation of ZIKV in the newborn can be applied.

Keywords: Zika; congenital infections; hepatitis B; neonatal herpes simplex infection; rubella.

PubMed Disclaimer

References

    1. Petersen LR, Jamieson DJ, Powers AM, Honein MA. Zika virus. N Engl J Med 2016; 374:1552–63. - PubMed
    1. Campos GS, Bandeira AC, Sardi SI. Zika virus outbreak, Bahia, Brazil. Emerg Infect Dis 2015; 21:1885–6. - PMC - PubMed
    1. Zanluca C, Melo VC, Mosimann AL, Santos GI, Santos CN, Luz K. First report of autochthonous transmission of Zika virus in Brazil. Mem Inst Oswaldo Cruz 2015; 110:569–72. - PMC - PubMed
    1. European Centre for Disease Prevention and Control. Rapid risk assessment: Zika virus epidemic in the Americas: potential association with microcephaly and Guillain-Barré syndrome. Solna, Sweden: ECDC, 2015.
    1. Fauci AS, Morens DM. Zika virus in the Americas—yet another arbovirus threat. N Engl J Med 2016; 374:601–4. - PubMed

Publication types

Supplementary concepts