United Again: STING and the Police
- PMID: 29268089
- DOI: 10.1016/j.neuron.2017.12.015
United Again: STING and the Police
Abstract
Neuroinflammation is a common feature of aging and neurodegeneration. In this issue of Neuron, Mathur et al. (2017) report that the antiviral drug Ganciclovir induces an interferon type I response in microglia through activation of the STING pathway, inhibiting inflammation and leading to protection in a model of multiple sclerosis.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation.Neuron. 2017 Dec 20;96(6):1290-1302.e6. doi: 10.1016/j.neuron.2017.11.032. Neuron. 2017. PMID: 29268096 Free PMC article.
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