ASCEND-5: too little too late?
- PMID: 29268320
- PMCID: PMC5723760
- DOI: 10.21037/jtd.2017.08.147
ASCEND-5: too little too late?
Conflict of interest statement
Conflicts of Interest: Dr. Wu has no conflicts of interest to declare. Prof. Ou has served as a compensated advisor to Pfizer, Roche/Genentech, Novartis, and ARIAD/Takeda.
Comment on
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Ceritinib versus chemotherapy in patients with ALK-rearranged non-small-cell lung cancer previously given chemotherapy and crizotinib (ASCEND-5): a randomised, controlled, open-label, phase 3 trial.Lancet Oncol. 2017 Jul;18(7):874-886. doi: 10.1016/S1470-2045(17)30339-X. Epub 2017 Jun 9. Lancet Oncol. 2017. PMID: 28602779 Clinical Trial.
References
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- Lu S, Mok T, Lu Y, et al. Phase 3 study of first-line crizotinib vs pemetrexed−cisplatin/carboplatin (PCC) in East Asian patients (pts) with ALK+ advanced non-squamous non-small cell lung cancer (NSCLC). J Clin Oncol 2016;34:abstr 9058.
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