Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017:2017:1483873.
doi: 10.1155/2017/1483873. Epub 2017 Nov 15.

Current Therapeutic Options for Heart Failure in Elderly Patients

Affiliations
Review

Current Therapeutic Options for Heart Failure in Elderly Patients

F Guerra et al. Biomed Res Int. 2017.

Abstract

Heart failure (HF) is a major and growing public health problem with high morbidity and mortality (Ponikowski et al., 2016). It affects 1-2% of the general population in developed countries, and the average age at diagnosis is 76 years. Because of a better management of acute phase and comorbidities, HF incidence is increasing in elderly patients, with a prevalence rising to 10% among people aged 65 years or older (Mozaffarian et al., 2014). Therefore, a substantial number of elderly patients need to be treated. However, because of clinical trial exclusion criteria or coexisting comorbidities, currently recommended therapies are widely based on younger population with a much lower mean age. In this review, we will focus on available pharmacological, electrical, and mechanical therapies, underlining pros, cons, and practical considerations of their use in this specific patient population.

PubMed Disclaimer

References

    1. Akita K., Kohno T., Kohsaka S., et al. Current use of guideline-based medical therapy in elderly patients admitted with acute heart failure with reduced ejection fraction and its impact on event-free survival. International Journal of Cardiology. 2017;235:162–168. doi: 10.1016/j.ijcard.2017.02.070. - DOI - PubMed
    1. Komajda M., Hanon O., Hochadel M., et al. Management of octogenarians hospitalized for heart failure in Euro Heart Failure Survey I. European Heart Journal. 2007;28(11):1310–1318. doi: 10.1093/eurheartj/ehl443. - DOI - PubMed
    1. Komajda M., Anker S. D., Cowie M. R., et al. Physicians' adherence to guideline-recommended medications in heart failure with reduced ejection fraction: Data from the QUALIFY global survey. European Journal of Heart Failure. 2016;18(5):514–522. doi: 10.1002/ejhf.510. - DOI - PubMed
    1. Cherubini A., Oristrell J., Pla X., et al. The persistent exclusion of older patients from ongoing clinical trials regarding heart failure. JAMA Internal Medicine. 2011;171(6):550–556. doi: 10.1001/archinternmed.2011.31. - DOI - PubMed
    1. Cioffi G., Stefenelli C., Tarantini L., Opasich C. Prevalence, predictors, and prognostic implications of improvement in left ventricular systolic function and clinical status in patients >70 years of age with recently diagnosed systolic heart failure. American Journal of Cardiology. 2003;92(2):166–172. doi: 10.1016/S0002-9149(03)00532-0. - DOI - PubMed