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. 1989 Feb 1;67(3):203-6.
doi: 10.1007/BF01711354.

Prognostic value of serum phospholipase A in the multitraumatized patient

C Waydhas  1 , D Nast-Kolb, K H Duswald, P Lehnert, L Schweiberer
Affiliations

Prognostic value of serum phospholipase A in the multitraumatized patient

C Waydhas et al. Klin Wochenschr. .

Abstract

Phospholipase A serum activity was prospectively studied in 39 patients with multiple trauma. There was no correlation of phospholipase A activity with type or severity of injury. With increasing phospholipase A levels, a rise in mortality was found. A prediction of fatal outcome on an individual basis was not possible. The sensitivity for complications was 90%, whereas the predictive value of the positive test (64%) and specificity (47%) were low. When the behavior of phospholipase A and elastase release were compared, no correlation between these two parameters could be detected. Therefore, PMN leukocytes do not seem to be a major source of phospholipase A in serum.

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