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. 2018 Mar:133:1-3.
doi: 10.1016/j.apradiso.2017.12.010. Epub 2017 Dec 9.

Production of curie quantities of 68Ga with a medical cyclotron via the 68Zn(p,n)68Ga reaction

Mai Lin  1 , Gregory J Waligorski  1 , Carlos González Lepera  2
Affiliations

Production of curie quantities of 68Ga with a medical cyclotron via the 68Zn(p,n)68Ga reaction

Mai Lin et al. Appl Radiat Isot. 2018 Mar.

Abstract

PET imaging with 68Ga-labeled tracers has seen a dramatic increase over the past five years primarily due to the increased accessibility of 68Ge/68Ga generators, the availability of tracers with superb targeting properties for labeling, straightforward labeling procedures and the approval of these tracers by regulatory entities. Available 68Ge/68Ga generators nominally deliver up to 1.85 GBq (50mCi) when fresh limiting production and distribution of 68Ga-labeled tracers to a few daily doses per generator. The focus of this study was to provide a simple and efficient method for 68Ga production in clinically relevant quantities using a low energy medical cyclotron with a solid target.

Keywords: (68)Ga; Automation; DOTA; PET.

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