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Review
. 2018 Mar;7(1):17-27.
doi: 10.1007/s40121-017-0183-9. Epub 2017 Dec 22.

Challenges and Solution of Invasive Aspergillosis in Non-neutropenic Patients: A Review

Matteo Bassetti  1 , Maddalena Peghin  2 , Antonio Vena  2
Affiliations
Review

Challenges and Solution of Invasive Aspergillosis in Non-neutropenic Patients: A Review

Matteo Bassetti et al. Infect Dis Ther. 2018 Mar.

Abstract

Invasive aspergillosis (IA) is a serious opportunistic infection, which has increasingly been recognized as an emerging disease of non-neutropenic patients. In this group of patients, the diagnosis of IA can be challenging owing to the lack of specificity of symptoms, the difficulty in discriminating colonization from infection, and the lower sensitivity of microbiological and radiological tests compared with immunocompromised patients. The aim of this article is to present to clinicians a critical review on the management of IA in non-neutropenic patients.

Keywords: Aspergillus; Biomarkers; Galactomannan; Invasive aspergillosis; Liver cirrhosis; Non-neutropenic patients.

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Figures

Fig. 1
Fig. 1
Diagnostic and therapeutic approach in non-neutropenic patients with suspected IA
See this image and copyright information in PMC

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