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Multicenter Study
. 2018 Mar;98(3):305-308.
doi: 10.1016/j.jhin.2017.12.016. Epub 2017 Dec 20.

Risk factors for imipenem-resistant Pseudomonas aeruginosa in neonatal intensive care units in south China

Y B Rao  1 , Z X Ren  1 , J J Zhong  2 , X M Zhong  1 , B Cao  3 , D M Chen  4 , X N Pan  5 , Y P Jia  6 , P M Gao  7 , B Y Yang  8 , Q Zhong  9 , J Yang  10 ; Collaborative Study Group of Neonatal Hospital Infection Control
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Free article
Multicenter Study

Risk factors for imipenem-resistant Pseudomonas aeruginosa in neonatal intensive care units in south China

Y B Rao et al. J Hosp Infect. 2018 Mar.
Free article

Abstract

This multi-centre retrospective study was designed to investigate the risk factors for infection with imipenem-resistant Pseudomonas aeruginosa in neonatal intensive care units (NICUs) in south China. All patients with confirmed P. aeruginosa infection from eight NICUs in south China were divided into two groups: imipenem-susceptible P. aeruginosa and imipenem-resistant P. aeruginosa. Data were analysed using Chi-squared test and logistic regression. In total, 188 medical records were reviewed. On multi-variate logistic analysis, the only independent risk factor was imipenem treatment within two weeks of isolation of P. aeruginosa (odds ratio 6.409, 95% confidence interval 1.926-21.333).

Keywords: Hospital-acquired infection; Imipenem; Neonate; Pseudomonas aeruginosa.

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