Ganglion blocks as a treatment of pain: current perspectives
- PMID: 29276402
- PMCID: PMC5734237
- DOI: 10.2147/JPR.S134775
Ganglion blocks as a treatment of pain: current perspectives
Abstract
The inputs from sympathetic ganglia have been known to be involved in the pathophysiology of various painful conditions such as complex regional pain syndrome, cancer pain of different origin, and coccygodynia. Sympathetic ganglia blocks are used to relieve patients who suffer from these conditions for over a century. Many numbers of local anesthetics such as bupivacaine or neurolytic agents such as alcohol can be chosen for a successful block. The agent is selected according to its duration of effect and the purpose of the injection. Most commonly used sympathetic blocks are stellate ganglion block, lumbar sympathetic block, celiac plexus block, superior hypogastric block, and ganglion Impar block. In this review, indications, methods, effectiveness, and complications of these blocks are discussed based on the data from the current literature.
Keywords: cancer pain; complex regional pain syndrome; ganglion; pain management; sympathetic nervous system.
Conflict of interest statement
Disclosure The authors report no conflicts of interest in this work.
Figures
References
-
- Drummond PD, Finch PM, Skipworth S, Blockey P. Pain increases during sympathetic arousal in patients with complex regional pain syndrome. Neurology. 2001;57(7):1296–1303. - PubMed
-
- Ramer MS, Bisby MA. Adrenergic innervation of rat sensory ganglia following proximal or distal painful sciatic neuropathy: distinct mechanisms revealed by anti-NGF treatment. Eur J Neurosci. 1999;11(3):837–846. - PubMed
-
- Jänig W, Baron R. Complex regional pain syndrome: mystery explained? Lancet Neurol. 2003;2(11):687–697. - PubMed
-
- Narouze S. Ultrasound-guided stellate ganglion block: safety and efficacy. Curr Pain Headache Rep. 2014;18(6):424. - PubMed
-
- Carron H, Litwiller R. Stellate ganglion block. Anesth Analg. 1975;54(5):567–570. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
