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Case Reports
. 2018 Jan 30;90(5):232-234.
doi: 10.1212/WNL.0000000000004890. Epub 2017 Dec 27.

COL4A1 and fetal vascular origins of schizencephaly

Roha Khalid  1 , Pradeep Krishnan  1 , Kathleen Andres  1 , Susan Blaser  1 , Steven Miller  1 , Mahendranath Moharir  1 , Nomazulu Dlamini  2
Affiliations
Case Reports

COL4A1 and fetal vascular origins of schizencephaly

Roha Khalid et al. Neurology. .
No abstract available

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Figures

Figure
Figure. Imaging series shows acute antenatal vascular disruption and the sequential development of schizencephaly
(A) Half-Fourier acquisition single-shot turbo spin echo images of the fetal brain at 21 weeks' gestation reveal increased signal intensity within the entire thickness of the cortical mantle with obscuration of the cortical layers in the affected zone. (B) Diffusion-weighted imaging of the fetal brain at 21 weeks' gestation shows areas of acute diffusion restriction within the right middle cerebral artery distribution. (C) Serial follow-up at 35 weeks' gestation reveals focal volume loss in the right cerebral hemisphere with parenchymal cleft extending to the ventricular margin. (D) Schizencephalic cleft lined by gray matter extending from the pial surface to the ventricular margin with focal tenting of the ventricular margin on postnatal imaging.
See this image and copyright information in PMC

References

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