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Editorial
. 2017 Oct 22;9(10):e1791.
doi: 10.7759/cureus.1791.

U-47700: An Emerging Threat

Affiliations
Editorial

U-47700: An Emerging Threat

Saeed K Alzghari et al. Cureus. .

Abstract

Illicit opioid use continues to be an ever-growing problem in the United States. The rise of synthetic opioids is an emerging threat that is beginning to draw attention over the past few years. Herein, we present an overview of the rise of a synthetic opioid known as U-47700. We describe U-47700's history, legal status, ease of obtainment, consequences of its use, and a proposal to increase the awareness of this synthetic opioid.

Keywords: drug abuse; novel psychoactive substance; opioid abuse; opioid poisoning; opioid toxidrome; opioids; synthetic opioid; u-47700.

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Conflict of interest statement

The authors have declared financial relationships, which are detailed in the next section.

Figures

Figure 1
Figure 1. Structure of U-47700
Figure 2
Figure 2. Physical sample of U-47700

References

    1. Increases in drug and opioid-involved overdose deaths - United States, 2010-2015. Rudd RA, Seth P, David F, Scholl L. MMWR Morb Mortal Wkly Rep. 2016;65:1445–1452. - PubMed
    1. Schedules of controlled substances: temporary placement of U-47700 into schedule I. Final order. Drug Enforcement Administration, Department of Justice. https://www.gpo.gov/fdsys/pkg/FR-2016-11-14/pdf/2016-27357.pdf. Fed Regist. 2016;81:79389–79393. - PubMed
    1. Two cases of intoxication with new synthetic opioid, U-47700. Domanski K, Kleinschmidt KC, Schulte JM, et al. Clin Toxicol (Phila) 2017;55:46–50. - PubMed
    1. U-47700: a clinical review of the literature. Rambaran KA, Fleming SW, An J, et al. J Emerg Med. 2017 - PubMed
    1. Analysis of U-47700, a novel synthetic opioid, in human urine by LC-MS-MS and LC-QToF. Fleming SW, Cooley JC, Johnson L, et al. J Anal Toxicol. 2017;41:173–180. - PubMed

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