Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1989 Mar;86(6):2018-20.
doi: 10.1073/pnas.86.6.2018.

Promotion of wound repair in old mice by local injection of macrophages

D Danon  1 , M A Kowatch, G S Roth
Affiliations
Comparative Study

Promotion of wound repair in old mice by local injection of macrophages

D Danon et al. Proc Natl Acad Sci U S A. 1989 Mar.

Abstract

Application of peritoneal macrophages to experimentally induced cutaneous wounds of old mice accelerates healing to levels almost comparable to those of untreated young animals. Slightly greater acceleration is observed when macrophages are obtained from young as opposed to old donors. These findings are consistent with a defect in macrophage function as a cause of impaired wound healing in senescence and suggest a possible therapeutic strategy.

PubMed Disclaimer

References

    1. Nature. 1967 Apr 29;214(5087):521-2 - PubMed
    1. Scand J Plast Reconstr Surg. 1972;6(1):24-35 - PubMed
    1. Am J Pathol. 1975 Jan;78(1):71-100 - PubMed
    1. Br J Ind Med. 1976 Feb;33(1):25-8 - PubMed
    1. Am J Pathol. 1976 Sep;84(3):501-14 - PubMed

Publication types