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. 2017 Nov 18;8(62):105936-105941.
doi: 10.18632/oncotarget.22511. eCollection 2017 Dec 1.

Elevated CEA is associated with worse survival in recurrent rectal cancer

Won Kyung Cho  1 , Doo Ho Choi  1 , Hee Chul Park  1 , Won Park  1 , Jeong Il Yu  1 , Young Suk Park  2 , Joon Oh Park  2 , Ho Yeong Lim  2 , Won Ki Kang  2 , Hee Cheol Kim  3 , Yong Beom Cho  3 , Seong Hyeon Yun  3 , Woo Yong Lee  3
Affiliations

Elevated CEA is associated with worse survival in recurrent rectal cancer

Won Kyung Cho et al. Oncotarget. .

Abstract

This study investigated the prognostic impact of serum carcinoembryonic antigen (CEA) level in recurrent rectal cancer. We reviewed 745 patients who developed recurrence after curative treatment for rectal cancer between January 2000 and December 2012. Multivariate analyses for survival revealed that age > 60 years (p = 0.005), r-CEA ≥ 5 ng/ml (p < 0.001), disease free interval (DFI) < 12 months (p < 0.001), and palliative or conservative treatment (p < 0.001) were unfavorable factors.

Keywords: CEA; rectal cancer; recurrence; survival.

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Conflict of interest statement

CONFLICTS OF INTEREST The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1. Survival after recurrence according to the CEA at the time of recurrence (r-CEA) level
See this image and copyright information in PMC

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