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. 2018 Feb 1;596(3):347-350.
doi: 10.1113/JP274944. Epub 2018 Jan 2.

CrossTalk proposal: an important astrocyte-to-neuron lactate shuttle couples neuronal activity to glucose utilisation in the brain

L F Barros  1 , B Weber  2
Affiliations

CrossTalk proposal: an important astrocyte-to-neuron lactate shuttle couples neuronal activity to glucose utilisation in the brain

L F Barros et al. J Physiol. .
No abstract available

Keywords: NADH; brain energy metabolism; glucose; glucose transport; glycolysis; lactate; lactate transport; neuron-glia interaction.

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Figures

Figure 1
Figure 1. Working model of glucose and lactate exchange between astrocytes and neurons
Dashed arrows connect the relevant pathways with the respective published work. For the sake of simplicity, only the main findings of the papers are considered. Please refer to the main text for details. We apologise to authors of relevant work that had to be omitted because of the maximum 30 references allowed by CrossTalk guidelines. GLUT1, GLUT3: glucose transporters GLUT1 and GLUT3; lac channel: lactate channel; MCT2, MCT4: monocarboxylate transporters MCT2 and MCT4; PPP: pentose phosphate pathway; PYR: pyruvate.
See this image and copyright information in PMC

Comment in

References

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