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. 2017 Jun 22;27(Suppl 3):18.
doi: 10.11604/pamj.supp.2017.27.3.11546. eCollection 2017.

Is hepatitis B birth dose vaccine needed in Africa?

Cynthia Raissa Tamandjou  1 , Tongai Gibson Maponga  1 , Nafiisah Chotun  1 , Wolfgang Preiser  1   2 , Monique Ingrid Andersson  1   3
Affiliations

Is hepatitis B birth dose vaccine needed in Africa?

Cynthia Raissa Tamandjou et al. Pan Afr Med J. .

Abstract

This commentary describes the need for a birth dose monovalent hepatitis B virus (HBV) vaccine and an effective programme for the prevention of mother-to-child-transmission (MTCT) of HBV in Africa. Current World Health Organization guidelines recommend routine maternal screening for HBV followed by treatment of highly infectious HBV-infected mothers, and HBV birth dose vaccination and the administration of hepatitis B immunoglobulin for HBV-exposed infants as an effective strategy for the prevention of HBV MTCT. None of these practices are currently in place in most parts of Africa. To date, fewer than 10 African countries vaccinate children at birth against HBV. Despite the hurdles associated with implementing this practice, its expansion to the rest of Africa is feasible and crucial to reducing the global number of new HBV infections by 90% by 2030, as targeted by the current Global Health Strategy for the elimination of viral hepatitis.

Keywords: Africa; HBV; birth-dose; elimination.

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Figures

Figure 1
Figure 1
Map of HBV birth dose vaccine and in-country coverage rates for 2015. Only nine African countries provide HBV birth dose vaccine and where provided, coverage needs to improve in order to achieve the recommended targets set by the WHO.
See this image and copyright information in PMC

References

    1. GBD 2013 Mortality and Causes of Death Collaborators Causes of Death, Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;385(9963):117–71. - PMC - PubMed
    1. Ferlay J, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 201. Int J Cancer. 2015;136(5):E359–86. - PubMed
    1. Hyams KC. Risks of chronicity following acute hepatitis B virus infection: a review. Clin Infect Dis. 1995;20(4):992–1000. - PubMed
    1. Shimakawa Y, et al. Natural history of chronic HBV infection in West Africa: a longitudinal population-based study from The Gambia. Gut. 2016;65(12):2007–2016. - PubMed
    1. Casey RM, et al. Global Routine Vaccination Coverage, 2015. MMWR Morb Mortal Wkly Rep. 2016;65(45):1270–1273. - PubMed

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