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. 2017 Oct 31:11:305-314.
doi: 10.2174/1874364101711010305. eCollection 2017.

A Single Drop in the Eye - Effects on the Whole Body?

Anu Vaajanen  1   2 , Heikki Vapaatalo  3
Affiliations

A Single Drop in the Eye - Effects on the Whole Body?

Anu Vaajanen et al. Open Ophthalmol J. .

Abstract

Introduction: Although the local adverse effects of ophthalmic drugs, including allergic reactions, are well recognized, less is known about the systemic side- effects of eye drops, especially during pregnancy, breast-feeding and early childhood. Ophthalmologists should also be aware of unusual, in some cases even life-threatening, effects of commonly used eye drops.

Conclusion: This brief review outlines the routes of systemic absorption and the kinetics of active components present in eye drops, and identifies the clinically relevant systemic adverse effects.

Keywords: Body; Eye; Kinetics; Ocular drugs; Ophthalmic drugs; Single drop.

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