Transfer of altered behaviour and irritable bowel syndrome with diarrhea (IBS-D) through fecal microbiota transplant in mouse model indicates need for stricter donor screening criteria

Laura J Craven^{1

2}, Michael Silverman^{1

2

3}, Jeremy P Burton^{1

2

4}

Affiliations

¹ Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
² Lawson Health Research Institute, London, ON, Canada.
³ Department of Infectious Disease, St. Joseph's Health Care, London, ON, Canada.
⁴ Division of Urology, Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

Editorial

Laura J Craven et al. Ann Transl Med. 2017 Dec.

. 2017 Dec;5(24):490.

doi: 10.21037/atm.2017.10.03.

Laura J Craven^{1

2}, Michael Silverman^{1

2

3}, Jeremy P Burton^{1

2

4}

¹ Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
² Lawson Health Research Institute, London, ON, Canada.
³ Department of Infectious Disease, St. Joseph's Health Care, London, ON, Canada.
⁴ Division of Urology, Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

No abstract available

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice.
De Palma G, Lynch MD, Lu J, Dang VT, Deng Y, Jury J, Umeh G, Miranda PM, Pigrau Pastor M, Sidani S, Pinto-Sanchez MI, Philip V, McLean PG, Hagelsieb MG, Surette MG, Bergonzelli GE, Verdu EF, Britz-McKibbin P, Neufeld JD, Collins SM, Bercik P. De Palma G, et al. Sci Transl Med. 2017 Mar 1;9(379):eaaf6397. doi: 10.1126/scitranslmed.aaf6397. Sci Transl Med. 2017. PMID: 28251905

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