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. 2018 Jan 3;97(1):10-13.
doi: 10.1016/j.neuron.2017.12.023.

Phase-Amplitude Coupling: A General Mechanism for Memory Processing and Synaptic Plasticity?

Til O Bergmann  1 , Jan Born  2
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Phase-Amplitude Coupling: A General Mechanism for Memory Processing and Synaptic Plasticity?

Til O Bergmann et al. Neuron. .
Free article

Abstract

In this issue of Neuron, Helfrich et al. (2017) demonstrate that phase-amplitude coupling (PAC) between slow oscillations and spindles is crucial for memory consolidation, and shifts in its phase relationship may explain age-related deficits in memory performance. These results also suggest a more general function of PAC in synaptic plasticity.

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