Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jan 4;6(1):e01401-17.
doi: 10.1128/genomeA.01401-17.

Draft Genome Sequence of Streptomyces sp. Strain JV178, a Producer of Clifednamide-Type Polycyclic Tetramate Macrolactams

Yunci Qi  1 , John M D'Alessandro  1 , Joshua A V Blodgett  2
Affiliations

Draft Genome Sequence of Streptomyces sp. Strain JV178, a Producer of Clifednamide-Type Polycyclic Tetramate Macrolactams

Yunci Qi et al. Genome Announc. .

Abstract

Here, we report the draft genome sequence of Streptomyces sp. JV178, a strain originating from Connecticut (USA) garden soil. This strain produces the polycyclic tetramate macrolactam compounds clifednamides A and B. The draft genome contains 10.65 Mb, 9,045 predicted protein coding sequences, and several natural product biosynthetic loci.

PubMed Disclaimer

References

    1. Challis GL, Hopwood DA. 2003. Synergy and contingency as driving forces for the evolution of multiple secondary metabolite production by Streptomyces species. Proc Natl Acad Sci U S A 100:14555–14561. doi:10.1073/pnas.1934677100. - DOI - PMC - PubMed
    1. Nett M, Ikeda H, Moore BS. 2009. Genomic basis for natural product biosynthetic diversity in the actinomycetes. Nat Prod Rep 26:1362–1384. doi:10.1039/b817069j. - DOI - PMC - PubMed
    1. Blodgett JA, Oh DC, Cao S, Currie CR, Kolter R, Clardy J. 2010. Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria. Proc Natl Acad Sci U S A 107:11692–11697. doi:10.1073/pnas.1001513107. - DOI - PMC - PubMed
    1. Cao S, Blodgett JAV, Clardy J. 2010. Targeted discovery of polycyclic tetramate macrolactams from an environmental Streptomyces strain. Org Lett 12:4652–4654. doi:10.1021/ol1020064. - DOI - PMC - PubMed
    1. Blodgett JAV, Zhang JK, Metcalf WW. 2005. Molecular cloning, sequence analysis, and heterologous expression of the phosphinothricin tripeptide biosynthetic gene cluster from Streptomyces viridochromogenes DSM 40736. Antimicrob Agents Chemother 49:230–240. doi:10.1128/AAC.49.1.230-240.2005. - DOI - PMC - PubMed

LinkOut - more resources