Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: flip side of the story
- PMID: 29302606
- PMCID: PMC5749412
- DOI: 10.14800/ics.1397
Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: flip side of the story
Keywords: Antacid therapy; gastroesophageal reflux; idiopathic pulmonary fibrosis; pirfenidone; proton pump inhibitors.
Conflict of interest statement
Conflicting interests YTG is an inventor on patents, owned by Stanford University, that protect the use of agents, including the PPIs, for therapeutic use of new indications including IPF. YTG is a cofounder of Altitude Pharma, Inc.; a biotechnology company developing PPI-based therapy for IPF.
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Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis.Lancet Respir Med. 2016 May;4(5):381-9. doi: 10.1016/S2213-2600(16)00067-9. Epub 2016 Mar 31. Lancet Respir Med. 2016. PMID: 27050871
References
-
- Raghu G, Freudenberger TD, Yang S, Curtis JR, Spada C, Hayes J, et al. High prevalence of abnormal acid gastro-oesophageal reflux in idiopathic pulmonary fibrosis. Eur Respir J. 2006;27:136–142. - PubMed
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- Linden PA, Gilbert RJ, Yeap BY, Boyle K, Deykin A, Jaklitsch MT, et al. Laparoscopic fundoplication in patients with end-stage lung disease awaiting transplantation. J Thorac Cardiovasc Surg. 2006;131:438–446. - PubMed
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- Raghu G, Yang ST, Spada C, Hayes J, Pellegrini CA. Sole treatment of acid gastroesophageal reflux in idiopathic pulmonary fibrosis: a case series. Chest. 2006;129:794–800. - PubMed
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- Lee JCH, Anstrom KJ, Martinez FJ, Noth I, Roberts RS, Yow E, Raghu G, for the IPFnet Investigators Anti-acid treatment and disease progression in idiopathic pulmonary fibrosis: an analysis of data from three randomised controlled trials. The Lancet Respiratory Medicine. 2013;1:369–376. - PMC - PubMed
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