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. 1989 Feb 1;257(3):917-9.
doi: 10.1042/bj2570917.

Adipsin mRNA amounts are not decreased in the genetically obese Zucker rat

I Dugail  1 , X Le Liepvre, A Quignard-Boulangé, J Pairault, M Lavau
Affiliations

Adipsin mRNA amounts are not decreased in the genetically obese Zucker rat

I Dugail et al. Biochem J. .

Abstract

Adipsin gene expression as assessed by mRNA amounts was examined in adipose tissue of genetically obese rats at the onset (16 days of age) or at later stages (30 and 60 days of age) of obesity. Amounts of mRNA were equivalent in obese and lean rats at 16 days of age. In adult rats, we observed a 2-fold decrease in adipsin mRNA in the obese rats compared with control lean rats, which was abolished by weaning the animals on a high-fat diet. Our data show that, in sharp contrast with genetically obese mice, adipsin mRNA is not suppressed in genetically obese Zucker rats.

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References

    1. Horm Metab Res. 1977 Jan;9(1):95-7 - PubMed
    1. Biochem J. 1988 Sep 1;254(2):483-7 - PubMed
    1. Physiol Rev. 1979 Jul;59(3):719-809 - PubMed
    1. J Lipid Res. 1982 Aug;23(6):839-49 - PubMed
    1. J Lipid Res. 1982 Aug;23(6):941-3 - PubMed