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Comment
. 2018 Feb;8(2):OF11.
doi: 10.1158/2159-8290.CD-RW2018-001. Epub 2018 Jan 5.

Determination of mTORC1 Complex Structures Reveals Regulatory Mechanisms

No authors listed
Comment

Determination of mTORC1 Complex Structures Reveals Regulatory Mechanisms

No authors listed. Cancer Discov. 2018 Feb.

Abstract

RHEB promotes allosteric activation of mTOR whereas PRAS40 blocks substrate recruitment sites.

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