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Review
. 2018 Feb 22;56(3):e01747-17.
doi: 10.1128/JCM.01747-17. Print 2018 Mar.

Assessing the Burden of Clostridium difficile Infection in Low- and Middle-Income Countries

G A Roldan  1 , A X Cui  1 , N R Pollock  2   3
Affiliations
Review

Assessing the Burden of Clostridium difficile Infection in Low- and Middle-Income Countries

G A Roldan et al. J Clin Microbiol. .

Abstract

In contrast to the significant resources invested in the diagnosis and prevention of Clostridium difficile infection (CDI) in resource-rich settings, in resource-limited settings patients with community- and hospital-acquired diarrhea may not routinely be tested for CDI. Is CDI actually less frequent or severe in resource-limited settings, or might we be missing an important opportunity to prevent CDI-related morbidity and mortality (and to promote antibiotic stewardship) in these settings? Here, we review the literature to assess the overall burden of CDI in low- and middle-income countries.

Keywords: C. difficile infection; CDI; Clostridioides; Clostridium difficile; global health; low income; middle income; resource limited.

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