Adalimumab concentration-based tapering strategy: as good as the recommended dosage
- PMID: 29306871
- PMCID: PMC5890625
- DOI: 10.1136/annrheumdis-2017-212376
Adalimumab concentration-based tapering strategy: as good as the recommended dosage
Keywords: anti-TNF; rheumatoid arthritis; treatment.
Conflict of interest statement
Competing interests: AB has received unrestricted grants from Pfizer, Roche and AbbVie and speaker fees from Pfizer, AbbVie, MSD, BMS, UCB, Novartis, Sandoz, Celltrion and Roche, and has acted as a consultant for Pfizer, Sandoz, Nordic, AbbVie, Roche, BMS, UCB and MSD. DM participated on behalf of his institution in clinical trials sponsored by AbbVie, Roche, BMS, Pfizer, UCB and MSD; his hospital received a grant for research from AbbVie in 2004 and from Nordic Pharma in 2012; he has acted as a consultant and given lectures on behalf of his institution for MSD, Novartis, UCB and Pfizer; he has been invited to attend international congresses by MSD, Roche, BMS, AbbVie and Janssen-Cilag.
Comment on
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Successful reduction of overexposure in patients with rheumatoid arthritis with high serum adalimumab concentrations: an open-label, non-inferiority, randomised clinical trial.Ann Rheum Dis. 2018 Apr;77(4):484-487. doi: 10.1136/annrheumdis-2017-211781. Epub 2017 Sep 22. Ann Rheum Dis. 2018. PMID: 28939629 Clinical Trial.
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