Review

. 2018 Feb 15:195:61-64.

doi: 10.1016/j.lfs.2018.01.002. Epub 2018 Jan 4.

Multifunctional capacity and therapeutic potential of lactoferrin

Luis Moreno-Expósito¹, Rebeca Illescas-Montes², Lucía Melguizo-Rodríguez³, Concepción Ruiz⁴, Javier Ramos-Torrecillas⁵, Elvira de Luna-Bertos⁶

Affiliations

¹ Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada (Spain), Avda, Ilustración, 60, 18016, Spain. Electronic address: almoreno@correo.ugr.es.
² Instituto Investigación Biosanitaria, ibs.Granada, C/Dr. Azpitarte 4 - 4ª planta, 18012 Granada, Spain; Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences (Melilla), University of Granada (Spain). Camino Cdad, De Málaga 22, 52005, Melilla, Spain. Electronic address: rebecaim@ugr.es.
³ Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada (Spain), Avda, Ilustración, 60, 18016, Spain; Instituto Investigación Biosanitaria, ibs.Granada, C/Dr. Azpitarte 4 - 4ª planta, 18012 Granada, Spain. Electronic address: luciamr@ugr.es.
⁴ Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada (Spain), Avda, Ilustración, 60, 18016, Spain; Instituto Investigación Biosanitaria, ibs.Granada, C/Dr. Azpitarte 4 - 4ª planta, 18012 Granada, Spain; Institute of Neuroscience Federico Olóriz, University of Granada, (Spain), Avda. del Conocimiento S/N, 18016, Armilla (Granada), Spain. Electronic address: crr@ugr.es.
⁵ Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada (Spain), Avda, Ilustración, 60, 18016, Spain; Instituto Investigación Biosanitaria, ibs.Granada, C/Dr. Azpitarte 4 - 4ª planta, 18012 Granada, Spain. Electronic address: jrt@ugr.es.
⁶ Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada (Spain), Avda, Ilustración, 60, 18016, Spain; Instituto Investigación Biosanitaria, ibs.Granada, C/Dr. Azpitarte 4 - 4ª planta, 18012 Granada, Spain. Electronic address: elviradlb@ugr.es.

PMID: 29307524
DOI: 10.1016/j.lfs.2018.01.002

Review

Multifunctional capacity and therapeutic potential of lactoferrin

Luis Moreno-Expósito et al. Life Sci. 2018.

. 2018 Feb 15:195:61-64.

doi: 10.1016/j.lfs.2018.01.002. Epub 2018 Jan 4.

Authors

Luis Moreno-Expósito¹, Rebeca Illescas-Montes², Lucía Melguizo-Rodríguez³, Concepción Ruiz⁴, Javier Ramos-Torrecillas⁵, Elvira de Luna-Bertos⁶

Affiliations

¹ Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada (Spain), Avda, Ilustración, 60, 18016, Spain. Electronic address: almoreno@correo.ugr.es.
² Instituto Investigación Biosanitaria, ibs.Granada, C/Dr. Azpitarte 4 - 4ª planta, 18012 Granada, Spain; Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences (Melilla), University of Granada (Spain). Camino Cdad, De Málaga 22, 52005, Melilla, Spain. Electronic address: rebecaim@ugr.es.
³ Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada (Spain), Avda, Ilustración, 60, 18016, Spain; Instituto Investigación Biosanitaria, ibs.Granada, C/Dr. Azpitarte 4 - 4ª planta, 18012 Granada, Spain. Electronic address: luciamr@ugr.es.
⁴ Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada (Spain), Avda, Ilustración, 60, 18016, Spain; Instituto Investigación Biosanitaria, ibs.Granada, C/Dr. Azpitarte 4 - 4ª planta, 18012 Granada, Spain; Institute of Neuroscience Federico Olóriz, University of Granada, (Spain), Avda. del Conocimiento S/N, 18016, Armilla (Granada), Spain. Electronic address: crr@ugr.es.
⁵ Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada (Spain), Avda, Ilustración, 60, 18016, Spain; Instituto Investigación Biosanitaria, ibs.Granada, C/Dr. Azpitarte 4 - 4ª planta, 18012 Granada, Spain. Electronic address: jrt@ugr.es.
⁶ Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada (Spain), Avda, Ilustración, 60, 18016, Spain; Instituto Investigación Biosanitaria, ibs.Granada, C/Dr. Azpitarte 4 - 4ª planta, 18012 Granada, Spain. Electronic address: elviradlb@ugr.es.

PMID: 29307524
DOI: 10.1016/j.lfs.2018.01.002

Abstract

Lactoferrin (LF) is a glycoprotein with high functional versatility that is found in most body fluids. The objective of this study was to gather and update information on the properties attributed to LF. According to this review, LF is a good immunomodulatory agent that acts on both innate and adaptive immune responses. It possesses antimicrobial activity against parasites, fungi, and viruses and also has regenerative properties at tissue level and anti-carcinogenic activity. All of these properties endow LF with major therapeutic potential of which little advantage has been taken to date.

Keywords: Anticancer activity; Antimicrobial agent; Immunomodulator; Lactoferrin; Tissue regenerator.

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Multifunctional capacity and therapeutic potential of lactoferrin

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