Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Dec 19:10:1178633717749597.
doi: 10.1177/1178633717749597. eCollection 2017.

Human Immunodeficiency Virus Resistance Testing Technologies and Their Applicability in Resource-Limited Settings of Africa

Idris Abdullahi Nasir  1   2   3 , Anthony Uchenna Emeribe  4 , Iduda Ojeamiren  5 , Hafeez Aderinsayo Adekola  1
Affiliations
Review

Human Immunodeficiency Virus Resistance Testing Technologies and Their Applicability in Resource-Limited Settings of Africa

Idris Abdullahi Nasir et al. Infect Dis (Auckl). .

Abstract

There has been tremendous breakthrough in the development of technologies and protocols for counselling, testing, and surveillance of resistant human immunodeficiency virus strains for efficient prognosis and clinical management aimed at improving the quality of life of infected persons. However, we have not arrived at a point where services rendered using these technologies can be made affordable and accessible to resource-limited settings. There are several technologies for monitoring antiretroviral resistance, each with unique merits and demerits. In this study, we review the strengths and limitations of prospective and affordable technologies with emphasis on those that could be used in resource-limited settings.

Keywords: Antiretroviral resistance; HIV/AIDS; laboratory technology.

PubMed Disclaimer

Conflict of interest statement

Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

References

    1. Centre for Disease Control and Prevention. HIV/AIDS. www.cdc.gov/hiv/default.html. Accessed July 20, 2017.
    1. De Clercq E. Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV. Int J Antimicrob Agents. 2009;33:307–320. - PubMed
    1. De Clercq E. Human viral diseases: what is next for antiviral drug discovery? Curr Opin Virol 2012;2:572–579. - PubMed
    1. World Health Organization. What’s new in treatment monitoring: viral load and CD4 testing. 2017. http://www.who.int/hiv/pub/arv/treatment-monitoring-info-2017/en/.
    1. Inzaule SC, Hamers RL, Paredes R, Yang C, Schuurman R, Rinke de Wit TF. The evolving landscape of HIV drug resistance diagnostics for expanding testing in resource-limited settings [published online ahead of print February 9, 2017]. AIDS Rev. PMID:28182618. - PubMed

LinkOut - more resources