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Editorial
. 2018 Feb 7;13(2):195-197.
doi: 10.2215/CJN.13791217. Epub 2018 Jan 8.

The Urine Anion Gap in Context

Affiliations
Editorial

The Urine Anion Gap in Context

Daniel Batlle et al. Clin J Am Soc Nephrol. .
No abstract available

Keywords: Acid-Base Equilibrium; Acidosis, Renal Tubular; Ammonium Chloride; Ammonium Compounds; Body Fluids; Humans; Hyperkalemia; Protons; Renal Insufficiency, Chronic; Sodium; acidosis; glomerular filtration rate.

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Figures

Figure 1.
Figure 1.
Urinary ammonium (NH4+) excretion in relation to urinary anion gap (UAG) for 38 patients with different types of distal renal tubular acidosis (blue circles), seven apparently healthy individuals receiving ammonium chloride (green circles), and eight patients with hyperchloremic metabolic acidosis associated with diarrhea (red triangles). Reprinted from ref. , with permission.

Comment on

References

    1. Goldstein MB, Bear R, Richardson RM, Marsden PA, Halperin ML: The urine anion gap: A clinically useful index of ammonium excretion. Am J Med Sci 292: 198–202, 1986 - PubMed
    1. Batlle DC, Hizon M, Cohen E, Gutterman C, Gupta R: The use of the urinary anion gap in the diagnosis of hyperchloremic metabolic acidosis. N Engl J Med 318: 594–599, 1988 - PubMed
    1. Batlle D, Haque SK: Genetic causes and mechanisms of distal renal tubular acidosis. Nephrol Dial Transplant 27: 3691–3704, 2012 - PubMed
    1. Palazzo V, Provenzano A, Becherucci F, Sansavini G, Mazzinghi B, Orlandini V, Giunti L, Roperto RM, Pantaleo M, Artuso R, Andreucci E, Bargiacchi S, Traficante G, Stagi S, Murer L, Benetti E, Emma F, Giordano M, Rivieri F, Colussi G, Penco S, Manfredini E, Caruso MR, Garavelli L, Andrulli S, Vergine G, Miglietti N, Mancini E, Malaventura C, Percesepe A, Grosso E, Materassi M, Romagnani P, Giglio S: The genetic and clinical spectrum of a large cohort of patients with distal renal tubular acidosis. Kidney Int 91: 1243–1255, 2017 - PubMed
    1. Batlle DC, Arruda JA, Kurtzman NA: Hyperkalemic distal renal tubular acidosis associated with obstructive uropathy. N Engl J Med 304: 373–380, 1981 - PubMed

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