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. 2017:2017:4521302.
doi: 10.1155/2017/4521302. Epub 2017 Nov 7.

Burden of Respiratory Syncytial Virus Hospitalizations in Canada

Ian Mitchell  1 , Isabelle Defoy  2 , ElizaBeth Grubb  3
Affiliations

Burden of Respiratory Syncytial Virus Hospitalizations in Canada

Ian Mitchell et al. Can Respir J. 2017.

Abstract

Objective: To examine the socioeconomic burden of respiratory syncytial virus (RSV) disease for Canadian infants hospitalized for the condition.

Data and methods: The descriptive study used data collected in Alberta, Canada, during 2 consecutive RSV seasons. Infants (<1 year of age) were included if they had not received palivizumab and were hospitalized with a confirmed diagnosis of RSV. Hospitalization resource use and parental time burden, out-of-pocket costs, lost work productivity, and stress and anxiety were assessed.

Results: 13.4% of all infants (n = 67) had intensive care unit (ICU) admission, and average ICU stay for these infants was 6.5 days. Families had average out-of-pocket expenses of 736.69 Canadian dollars (CAD $), and the average time both parents spent in hospital was nearly 7 days (164.0 hours). For working parents (n = 43), average absenteeism was 49% and overall work impairment was 77.8%. Parents also exhibited significant parental stress (3.6 on the Parental Stressor Scale: 43.9 state anxiety and 36.9 trait anxiety scores).

Conclusions: Results indicate a high burden associated with the hospitalization of an infant due to RSV disease in terms of resource use, time, productivity, costs, and stress, even among a population of infants not considered to be at risk for the condition.

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Figures

Figure 1
Figure 1
Healthcare resource utilization—by term status. (a) Use of supplemental oxygen. (b) Intensive care admission. Sample size: all infants (N = 67), term infants (N = 54), and preterm infants (N = 13).
Figure 2
Figure 2
Hospital length of stay (LOS)—by term status. Sample size: hospital (N = 67): 54 term infants and 13 preterm infants. Pediatric ward (N = 66): 54 term infants and 12 preterm infants. Intensive care unit (N = 9): 7 term infants and 2 preterm infants.
Figure 3
Figure 3
WPAI-CHRI. Sample size: both working parents (N = 43), working fathers (N = 37), and working mothers (N = 6).
Figure 4
Figure 4
Parental stress and anxiety. (a) Parental stressor scale. (b) State-trait anxiety inventory. Sample size: both working parents (N = 43), working fathers (N = 37), and working mothers (N = 6).
See this image and copyright information in PMC

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