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Review
. 2018 Jan 9;7(1):9.
doi: 10.3390/jcm7010009.

The Evolving Treatment of Peripheral Arterial Disease through Guideline-Directed Recommendations

Ramez Morcos  1 , Boshra Louka  2 , Andrew Tseng  3 , Sanjay Misra  4 , Robert McBane  5 , Heidi Esser  6 , Fadi Shamoun  7
Affiliations
Review

The Evolving Treatment of Peripheral Arterial Disease through Guideline-Directed Recommendations

Ramez Morcos et al. J Clin Med. .

Abstract

Peripheral arterial disease (PAD) refers to partial or complete occlusion of one or more non-coronary arteries that leads to compromised blood flow and ischemia. Numerous processes are involved in arterial stenosis, however, atherosclerosis remains the most common etiology. PAD constitutes a major health economic problem, and it is estimated that over 200 million people around the world suffer from PAD, with at least 20% having some degree of claudication. The purpose of this review is to compare and contrast the guidelines on PAD published in 2005, 2011 and 2016 in terms of new recommendations and level of evidence for practicing clinicians.

Keywords: ankle brachial index; claudication; guidelines; peripheral arterial disease.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Comparison between guidelines 2011 and 2016 in terms of class of recommendations (COR) and level of evidence (LOE).
See this image and copyright information in PMC

References

    1. Criqui M.H., Aboyans V. Epidemiology of peripheral artery disease. Circ. Res. 2015;116:1509–1526. doi: 10.1161/CIRCRESAHA.116.303849. - DOI - PubMed
    1. Olin J.W., Sealove B.A. Peripheral artery disease: Current insight into the disease and its diagnosis and management. Mayo Clin. Proc. 2010;85:678–692. doi: 10.4065/mcp.2010.0133. - DOI - PMC - PubMed
    1. Rose G.A. The diagnosis of ischaemic heart pain and intermittent claudication in field surveys. Bull. World Health Organ. 1962;27:645–658. - PMC - PubMed
    1. Fowkes F.G., Rudan D., Rudan I., Aboyans V., Denenberg J.O., McDermott M.M., Norman P.E., Sampson U.K.A., Williams L.J., Mensah G.A., et al. Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: A systematic review and analysis. Lancet. 2013;382:1329–1340. doi: 10.1016/S0140-6736(13)61249-0. - DOI - PubMed
    1. Hiatt W.R. Medical treatment of peripheral arterial disease and claudication. N. Engl. J. Med. 2001;344:1608–1621. doi: 10.1056/NEJM200105243442108. - DOI - PubMed

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