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Comment
. 2018 Jan 8;28(1):R30-R33.
doi: 10.1016/j.cub.2017.10.067.

LPS Transport: Flipping Out over MsbA

Bradley J Voss  1 , M Stephen Trent  2
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Comment

LPS Transport: Flipping Out over MsbA

Bradley J Voss et al. Curr Biol. .
Free article

Abstract

Lipopolysaccharide synthesis and transport pathways are attractive targets for the development of new antimicrobial therapeutics. The ABC (ATP Binding Cassette) transporter MsbA has been recently described as employing a 'trap and flip' mechanism of lipopolysaccharide transport. This represents a novel mechanism amongst known lipid ABC transporters.

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