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. 2018 Jan 8;33(1):5-7.
doi: 10.1016/j.ccell.2017.12.005.

What's in a Name? Cell Fate Reprogramming in Sarcomagenesis

Kevin B Jones  1
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What's in a Name? Cell Fate Reprogramming in Sarcomagenesis

Kevin B Jones. Cancer Cell. .
Free article

Abstract

Differentiation features in cancer cells are typically attributed to the cell of origin. In this issue of Cancer Cell, Drummond et al. demonstrate a transdifferentiation program apparent in rhabdomyosarcomas (cancers with skeletal muscle differentiation features) arising through cell fate reprogramming from a single oncogene activation in endothelial cell precursors.

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