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. 2018 Jan 9;13(1):2.
doi: 10.1186/s11671-017-2405-1.

Fabrication, Characterization, and Biological Activity of Avermectin Nano-delivery Systems with Different Particle Sizes

Anqi Wang  1   2 , Yan Wang  3   4 , Changjiao Sun  1   2 , Chunxin Wang  1   2 , Bo Cui  1   2 , Xiang Zhao  1   2 , Zhanghua Zeng  1   2 , Junwei Yao  1   2 , Dongsheng Yang  1   2 , Guoqiang Liu  1   2 , Haixin Cui  5   6
Affiliations

Fabrication, Characterization, and Biological Activity of Avermectin Nano-delivery Systems with Different Particle Sizes

Anqi Wang et al. Nanoscale Res Lett. .

Abstract

Nano-delivery systems for the active ingredients of pesticides can improve the utilization rates of pesticides and prolong their control effects. This is due to the nanocarrier envelope and controlled release function. However, particles containing active ingredients in controlled release pesticide formulations are generally large and have wide size distributions. There have been limited studies about the effect of particle size on the controlled release properties and biological activities of pesticide delivery systems. In the current study, avermectin (Av) nano-delivery systems were constructed with different particle sizes and their performances were evaluated. The Av release rate in the nano-delivery system could be effectively controlled by changing the particle size. The biological activity increased with decreasing particle size. These results suggest that Av nano-delivery systems can significantly improve the controllable release, photostability, and biological activity, which will improve efficiency and reduce pesticide residues.

Keywords: Avermectin; Biological activity; Controlled release; Nano-delivery system.

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Conflict of interest statement

Authors’ Information

AW, CW, and JY are PhD students; CS and XZ are assistant professors; YW and BC are associate professors; HC, GL, and ZZ are professors; DY is a graduate student in the Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences.

Competing Interests

The authors declare that they have no competing interests.

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Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Schematic showing the preparation of the Av nano-delivery system
Fig. 2
Fig. 2
SEM images (a–d) and size distributions (e) of Av nano-delivery systems with different particle sizes
Fig. 3
Fig. 3
Amounts of Av in Av nano-delivery systems with different particle sizes
Fig. 4
Fig. 4
Release behaviors of Av nano-delivery systems with different particle sizes in ethanol/water (50:50, v/v) over 200 h
Fig. 5
Fig. 5
Bioassay results of Av nano-delivery systems with different particle sizes
Fig. 6
Fig. 6
Comparison of Av photolysis percentage with the commercial WDG and nano-delivery system under UV irradiation
Fig. 7
Fig. 7
Stability of Av nano-delivery system at different storage temperatures
See this image and copyright information in PMC

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