Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Aug;22(3):561-573.
doi: 10.1007/s11030-017-9809-9. Epub 2018 Jan 9.

Synthesis of functionalized dihydro-2-oxopyrroles using graphene oxide as heterogeneous catalyst

Masoumeh Bavadi  1 , Khodabakhsh Niknam  2
Affiliations

Synthesis of functionalized dihydro-2-oxopyrroles using graphene oxide as heterogeneous catalyst

Masoumeh Bavadi et al. Mol Divers. 2018 Aug.

Abstract

A mild, efficient synthetic approach for the synthesis of highly functionalized dihydro-2-oxopyrroles is developed by using graphene oxide, a readily available and inexpensive material, as an eco-benign solid acid catalyst in ethanol at room temperature. The present methodology displays several advantages such as practical simplicity, high atom economy, easy workup procedure, and high yields of the products.

Keywords: Dihydro-2-oxopyrroles; Eco-friendly conditions; Graphene oxide; Heterogeneous catalyst; MCRs; Synthesis.

PubMed Disclaimer

References

    1. J Org Chem. 2009 Oct 2;74(19):7457-63 - PubMed
    1. J Nanosci Nanotechnol. 2015 Mar;15(3):1984-2000 - PubMed
    1. Drug Metab Dispos. 2015 Apr;43(4):459-66 - PubMed
    1. Chem Soc Rev. 2012 Feb 21;41(4):1452-61 - PubMed
    1. J Antibiot (Tokyo). 2016 Mar;69(3):133-40 - PubMed

LinkOut - more resources