Cancer chemoprevention and therapy using chinese herbal medicine

Lijing Jiao^#^{1

2}, Ling Bi^#², Yan Lu², Qin Wang², Yabin Gong², Jun Shi², Ling Xu²

Affiliations

¹ Institute of Clinical Immunology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437 China.
² Department of Oncology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, No.110, Ganhe Road, Hongkou District, Shanghai, 200437 China.

^# Contributed equally.

PMID: 29321719
PMCID: PMC5757296
DOI: 10.1186/s12575-017-0066-1

Review

Cancer chemoprevention and therapy using chinese herbal medicine

Lijing Jiao et al. Biol Proced Online. 2018.

. 2018 Jan 8:20:1.

doi: 10.1186/s12575-017-0066-1. eCollection 2018.

Authors

Lijing Jiao^#^{1

2}, Ling Bi^#², Yan Lu², Qin Wang², Yabin Gong², Jun Shi², Ling Xu²

Affiliations

¹ Institute of Clinical Immunology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437 China.
² Department of Oncology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, No.110, Ganhe Road, Hongkou District, Shanghai, 200437 China.

^# Contributed equally.

PMID: 29321719
PMCID: PMC5757296
DOI: 10.1186/s12575-017-0066-1

Abstract

Traditional Chinese medicine (TCM) plays an indispensable role in cancer prevention and treatment. Chinese herbal medicine (CHM) is a key component of TCM and has been practiced for thousands of years. A number of naturally occurring products from Chinese herbs extracts exhibit strong inhibitory properties against carcinogenesis, including CHM single-herb extracts, CHM-derived active components, and CHM formulas (the polyherbal combinations), which regulate JAK/STAT, MAPK, and NF-ҡB pathways. The present review aims to report the cancer-preventive effect of CHM with evidence from cell-line, animal, epidemiological, and clinical experiments. We also present several issues that have yet to be resolved. In the future, cancer prevention by CHM will face unprecedented opportunities and challenges.

Keywords: Cancer; Chemoprevention; Chinese herbal medicine; Treatment.

PubMed Disclaimer

Conflict of interest statement

Not applicable.Not applicable.The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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Cancer chemoprevention and therapy using chinese herbal medicine

Affiliations

Cancer chemoprevention and therapy using chinese herbal medicine

Authors

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Abstract

Conflict of interest statement

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