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Review
. 2018 Jan 8:20:1.
doi: 10.1186/s12575-017-0066-1. eCollection 2018.

Cancer chemoprevention and therapy using chinese herbal medicine

Lijing Jiao #  1   2 , Ling Bi #  2 , Yan Lu  2 , Qin Wang  2 , Yabin Gong  2 , Jun Shi  2 , Ling Xu  2
Affiliations
Review

Cancer chemoprevention and therapy using chinese herbal medicine

Lijing Jiao et al. Biol Proced Online. .

Abstract

Traditional Chinese medicine (TCM) plays an indispensable role in cancer prevention and treatment. Chinese herbal medicine (CHM) is a key component of TCM and has been practiced for thousands of years. A number of naturally occurring products from Chinese herbs extracts exhibit strong inhibitory properties against carcinogenesis, including CHM single-herb extracts, CHM-derived active components, and CHM formulas (the polyherbal combinations), which regulate JAK/STAT, MAPK, and NF-ҡB pathways. The present review aims to report the cancer-preventive effect of CHM with evidence from cell-line, animal, epidemiological, and clinical experiments. We also present several issues that have yet to be resolved. In the future, cancer prevention by CHM will face unprecedented opportunities and challenges.

Keywords: Cancer; Chemoprevention; Chinese herbal medicine; Treatment.

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Conflict of interest statement

Not applicable.Not applicable.The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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